Products of digestion in the gut are derived from animal products high in fat is known to increase the risk of heart disease. In a recent study known food is also associated with chronic kidney disease.
Researchers at the Cleveland Clinic observed that elevated levels of Trimethylamine N-oxide (TMAO) in a person's blood could help predict whether he will be at risk of suffering from chronic kidney failure or not.
In a separate part of this study, by using animals, the researchers found that a diet rich in TMAO the kidney in rats become weak and this compound will be accumulated, so mepercepat development of chronic kidney disease and heart disease.
"It shows us that TMAO is a mediator of cardiovascular disease and now seems to be a mediator in the development of chronic kidney," said Stanley Hazen, chairman of the department of molecular medicine at the Lerner Research Institute, Cleveland Clinic.
On the other hand, a person suffering from chronic kidney disease are also at high risk of heart disease. "The worse the kidney function, the higher TMAO in the can," he said.
TMAO is formed when the digestive system metabolize foods such as red meat, veal, and egg yolks.
Previous research has linked TMAO with atherosclerosis or pack buildup in blood vessels. Over time, this plaque will clog arteries and cause heart attacks or strokes.
However, this study only found a link in mice. Not necessarily the same effect is also seen in humans. Therefore the researchers will now continue his research to determine whether certain dietary changes can prevent the formation of TMAO and prevent kidney disease. (Monica Erisanti)
Researchers at the Cleveland Clinic observed that elevated levels of Trimethylamine N-oxide (TMAO) in a person's blood could help predict whether he will be at risk of suffering from chronic kidney failure or not.
In a separate part of this study, by using animals, the researchers found that a diet rich in TMAO the kidney in rats become weak and this compound will be accumulated, so mepercepat development of chronic kidney disease and heart disease.
"It shows us that TMAO is a mediator of cardiovascular disease and now seems to be a mediator in the development of chronic kidney," said Stanley Hazen, chairman of the department of molecular medicine at the Lerner Research Institute, Cleveland Clinic.
On the other hand, a person suffering from chronic kidney disease are also at high risk of heart disease. "The worse the kidney function, the higher TMAO in the can," he said.
TMAO is formed when the digestive system metabolize foods such as red meat, veal, and egg yolks.
Previous research has linked TMAO with atherosclerosis or pack buildup in blood vessels. Over time, this plaque will clog arteries and cause heart attacks or strokes.
However, this study only found a link in mice. Not necessarily the same effect is also seen in humans. Therefore the researchers will now continue his research to determine whether certain dietary changes can prevent the formation of TMAO and prevent kidney disease. (Monica Erisanti)
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